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New pyranonaphthazarin and 2-naphthoic acid derivatives from the mangrove endophytic fungus Leptosphaerulina sp. SKS032
- Source :
- Phytochemistry Letters. 20:214-217
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- Two new compounds, named leptospyranonaphthazarin A ( 1 ) and leptosnaphthoic acid A ( 2 ), together with four known compounds ( 3–6 ) were isolated from an endophytic fungus Leptosphaerulina sp. SKS032. Their structures were assigned using spectroscopic methods, computational methods, and single-crystal X-ray diffraction analysis. In the antibiotic assay, compounds 1 , 2 , and 6 exhibited antibacterial activities against Staphylococcus aureus with minimal inhibitory concentration (MIC) values of 25.0, 50.0, and 50.0 μg/mL, respectively.
- Subjects :
- 010405 organic chemistry
medicine.drug_class
Stereochemistry
Chemical structure
Antibiotics
Leptosphaerulina sp
Plant Science
Biology
Endophytic fungus
010402 general chemistry
medicine.disease_cause
01 natural sciences
Biochemistry
0104 chemical sciences
Minimum inhibitory concentration
Staphylococcus aureus
medicine
Mangrove
Naphthoic acid
Agronomy and Crop Science
Biotechnology
Subjects
Details
- ISSN :
- 18743900
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Phytochemistry Letters
- Accession number :
- edsair.doi...........1e90fe44cd78e0a63840dddfb1174eac