Synthesis, crystal structure and in silico studies of novel 2,4-dimethoxy-tetrahydropyrimido[4,5-b]quinolin-6(7H)-ones

Authors :: Subham G. Patel
Ruturajsinh M. Vala
Paras J. Patel
Dipti B. Upadhyay
V. Ramkumar
Ramesh L. Gardas
Hitendra M. Patel
Source :: RSC Advances. 12:18806-18820
Publication Year :: 2022
Publisher :: Royal Society of Chemistry (RSC), 2022.
Abstract: Single-crystal XRD analysis of 2,4-dimethoxy THPQs and their relative reactivity with properties were investigated using DFT calculation. Molecular docking studies show they effectively docked with main protease of SARS-CoV-2.

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