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Infection triggers symptoms similar to those of Parkinson’s disease in mice lacking PINK1 protein

Authors :
Malú G. Tansey
Mary K. Herrick
Source :
Nature. 571:481-482
Publication Year :
2019
Publisher :
Springer Science and Business Media LLC, 2019.

Abstract

In mice lacking a protein genetically linked to Parkinson’s disease, an autoimmune response to gut infection compromises the function of dopamine-producing neurons and leads to transient movement impairments. Infected mice lacking PINK1 protein show transient motor deficits.

Details

ISSN :
14764687 and 00280836
Volume :
571
Database :
OpenAIRE
Journal :
Nature
Accession number :
edsair.doi...........2163c3422811c81f682ba034275801a9
Full Text :
https://doi.org/10.1038/d41586-019-02094-6