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Infection triggers symptoms similar to those of Parkinson’s disease in mice lacking PINK1 protein
- Source :
- Nature. 571:481-482
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- In mice lacking a protein genetically linked to Parkinson’s disease, an autoimmune response to gut infection compromises the function of dopamine-producing neurons and leads to transient movement impairments. Infected mice lacking PINK1 protein show transient motor deficits.
Details
- ISSN :
- 14764687 and 00280836
- Volume :
- 571
- Database :
- OpenAIRE
- Journal :
- Nature
- Accession number :
- edsair.doi...........2163c3422811c81f682ba034275801a9
- Full Text :
- https://doi.org/10.1038/d41586-019-02094-6