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Health Claims on the Benefits of Moderate Alcohol Consumption in Relation to Genetic Profiles
- Source :
- Journal of Wine Research. 22:123-129
- Publication Year :
- 2011
- Publisher :
- Informa UK Limited, 2011.
-
Abstract
- A total of 43 individuals were included in a study of genetic and environmental factors associated with cardiovascular disease; seven subjects (16%) were diagnosed with the metabolic syndrome. A statistically significant association was observed between the E2 allele of the apolipoprotein E (Apo E) polymorphism and an increasing number of metabolic syndrome features (p = 0.03). Clinical and biochemical abnormalities identified could be ascribed to the combined effects of unfavorable genotypes and environmental factors known to interact with the Apo E gene. Excessive alcohol intake, high-calorie diets and smoking should be restricted in individuals with the Apo E2 and/or E4 alleles, which are associated with a significantly increased risk of cardiovascular disease.
Details
- ISSN :
- 14699672 and 09571264
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Journal of Wine Research
- Accession number :
- edsair.doi...........21a640957c93a03c479cadc7261392a4