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Pharmacological evaluation of methanolic extract of Cyperus scariosus

Authors :
Muhammad Waqas Khan
Mushtaq Ahmed
Rahmat Ali Khan
Latif Ullah Khan
Wasi Ullah Khan
Source :
Bangladesh Journal of Pharmacology. 11:353
Publication Year :
2016
Publisher :
Bangladesh Journals Online (JOL), 2016.

Abstract

The present study is aimed to investigate the phytochemical screening and biological activities of methanolic extract of Cyperus scariosus roots. Dried plant was grounded and extracted with methanol to prepare methanol crud extract. In vitro biological tests were conducted using this methanolic extracts according to the standard procedure. 100% death rate of brine shrimp was perceived at 3 mg/mL of plant extract after 72 hours. The extract showed action against Aspergillus flavius i.e. 90% followed by A. niger (91%) while the highest activity was shown against A. fumegatrus (94%). Important scavenging results were detected during scavenging of free radicals viz; 92.2% against DPPH, 82.2% to ABTS, 75.8% to hydrogen peroxide, 88.1% to β-carotene, 86.1% to hydroxyl radical and 89.4% against phosphomolybdate at 3 mg/mL were obtained. The results obtained in this study point out that extract showed significant biological activities which might be due to the presence of bioactive constituents.

Details

ISSN :
19910088
Volume :
11
Database :
OpenAIRE
Journal :
Bangladesh Journal of Pharmacology
Accession number :
edsair.doi...........21d5930ae99f39e093e8f7c208c6acf5
Full Text :
https://doi.org/10.3329/bjp.v11i2.23611