Back to Search
Start Over
Pharmacological evaluation of methanolic extract of Cyperus scariosus
- Source :
- Bangladesh Journal of Pharmacology. 11:353
- Publication Year :
- 2016
- Publisher :
- Bangladesh Journals Online (JOL), 2016.
-
Abstract
- The present study is aimed to investigate the phytochemical screening and biological activities of methanolic extract of Cyperus scariosus roots. Dried plant was grounded and extracted with methanol to prepare methanol crud extract. In vitro biological tests were conducted using this methanolic extracts according to the standard procedure. 100% death rate of brine shrimp was perceived at 3 mg/mL of plant extract after 72 hours. The extract showed action against Aspergillus flavius i.e. 90% followed by A. niger (91%) while the highest activity was shown against A. fumegatrus (94%). Important scavenging results were detected during scavenging of free radicals viz; 92.2% against DPPH, 82.2% to ABTS, 75.8% to hydrogen peroxide, 88.1% to β-carotene, 86.1% to hydroxyl radical and 89.4% against phosphomolybdate at 3 mg/mL were obtained. The results obtained in this study point out that extract showed significant biological activities which might be due to the presence of bioactive constituents.
- Subjects :
- 0106 biological sciences
Pharmacology
ABTS
Traditional medicine
biology
DPPH
Brine shrimp
biology.organism_classification
030226 pharmacology & pharmacy
01 natural sciences
Cyperus scariosus
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
chemistry
Phytochemical
010608 biotechnology
Hydroxyl radical
Methanol
Hydrogen peroxide
Subjects
Details
- ISSN :
- 19910088
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- Bangladesh Journal of Pharmacology
- Accession number :
- edsair.doi...........21d5930ae99f39e093e8f7c208c6acf5
- Full Text :
- https://doi.org/10.3329/bjp.v11i2.23611