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Doxazosin Free-Base Structure Determination and Its Equilibrium Solubility Compared to Polymorphic Doxazosin Mesylate Forms A and H
- Source :
- Crystal Growth & Design. 19:737-746
- Publication Year :
- 2019
- Publisher :
- American Chemical Society (ACS), 2019.
-
Abstract
- Doxazosin mesylate (DM) is a class II drug in the Biopharmaceutics Classification System (BCS) that is used in several types of hypertension treatments. DM presents almost 20 different polymorphs d...
- Subjects :
- Drug
Hypertension treatment
010405 organic chemistry
Chemistry
media_common.quotation_subject
Free base
General Chemistry
Pharmacology
urologic and male genital diseases
010402 general chemistry
Condensed Matter Physics
Biopharmaceutics Classification System
01 natural sciences
Doxazosin Mesylate
0104 chemical sciences
Doxazosin
medicine
General Materials Science
Solubility
media_common
medicine.drug
Subjects
Details
- ISSN :
- 15287505 and 15287483
- Volume :
- 19
- Database :
- OpenAIRE
- Journal :
- Crystal Growth & Design
- Accession number :
- edsair.doi...........21d7c4b19a6397a0530c1b96baf99857
- Full Text :
- https://doi.org/10.1021/acs.cgd.8b01323