Levoglucosenone-derived precursors for the stereoselective synthesis of methylene-expanded analogues of C-nucleosides

Authors :: Valery K. Brel
Adam I. Stash
A. V. Samet
Leonid D. Konyushkin
Victor V. Semenov
Vitaly K. Belsky
Source :: Mendeleev Communications. 25:44-46
Publication Year :: 2015
Publisher :: Elsevier BV, 2015.
Abstract: Simple chiral precursors for the preparation of methylene-expanded C-nucleosides were developed, using as key steps pyrolysis of cellulose to levoglucosenone followed by hydrogenation and introduction of vinyl and ethynyl fragments to the 2-position.

Subjects :: chemistry.chemical_compound
chemistry
organic chemicals
technology, industry, and agriculture
Organic chemistry
Stereoselectivity
General Chemistry
C nucleosides
Cellulose
Methylene
Pyrolysis

Tools