Genomics in Gynecological Cancer: Future Perspective

All cancers arise as a result of dynamic changes in the cancer genome. Cancer cells show diverse biological capabilities that are conferred by numerous genetic and epigenetic changes. Over the past years, comprehensive genomic studies using next-generation sequencing technology have resulted in an increasing wealth of the understanding of molecular mechanisms with respect to the genomic features of gynecological malignancies, including ovarian, endometrial, and cervical cancers. These studies can be exploited to develop and improve cancer classification, new diagnostic methods, and novel therapeutic strategies.