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Vitamin E Succinic Acid enhances the effect of mDRA-6 to eradicate leukemia cells by inducing apoptosis
- Source :
- The Chinese-German Journal of Clinical Oncology. 11:187-191
- Publication Year :
- 2012
- Publisher :
- Springer Science and Business Media LLC, 2012.
-
Abstract
- Objective The aim of our study was to detect whether Vitamin E Succinic Acid (VES) could regulate the expression level of DR5 in the cells and further elucidate the potential mechanisms involving that VES enhances the effect of mDRA-6 to eradicate leukemia Raji and K562 cells.
- Subjects :
- medicine.drug_class
Vitamin E
medicine.medical_treatment
chemical and pharmacologic phenomena
TNF-Related Apoptosis-Inducing Ligand
Biology
medicine.disease
Monoclonal antibody
chemistry.chemical_compound
Leukemia
Oncology
Biochemistry
chemistry
Succinic acid
Apoptosis
hemic and lymphatic diseases
TNFRSF10B
medicine
Cancer research
K562 cells
Subjects
Details
- ISSN :
- 16139089 and 16101979
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- The Chinese-German Journal of Clinical Oncology
- Accession number :
- edsair.doi...........24ce089d1570971da838115d559c0bf4
- Full Text :
- https://doi.org/10.1007/s10330-011-0922-4