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Kategorisierung der Tumoren der Cervix uteri
- Source :
- Der Pathologe. 37:573-584
- Publication Year :
- 2016
- Publisher :
- Springer Science and Business Media LLC, 2016.
-
Abstract
- In the 2014 WHO classification, squamous cell precursor lesions are classified as low-grade and high-grade intraepithelial lesions. LSIL corresponds to CIN1, HSIL includes CIN2 and CIN3. Only adenocarcinoma in situ (AIS) is accepted as precursor of adenocarcinoma and includes the stratified mucin-producing intraepithelial lesion (SMILE). Although relatively rare, adenocarcinoma and squamous cell carcinoma can be mixed with a poorly differentiated neuroendocrine carcinoma. Most cervical adenocarcinomas are low grade and of endocervical type. Mucinous carcinomas show marked intra- and extracellular mucin production. Almost all squamous cell carcinomas, the vast majority of adenocarcinomas, and many rare carcinoma types are HPV related. For low grade endocervical adenocarcinomas, the pattern-based classification according to Silva should be reported. Neuroendocrine tumors are rare and are classified into low-grade and high-grade, whereby the term carcinoid is still used.
- Subjects :
- 0301 basic medicine
Pathology
medicine.medical_specialty
Neoplasm Grading
business.industry
Carcinoma in situ
Mucin
Neuroendocrine tumors
medicine.disease
Cervical intraepithelial neoplasia
Pathology and Forensic Medicine
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
030220 oncology & carcinogenesis
Carcinoma
medicine
Immunohistochemistry
Adenocarcinoma
business
Subjects
Details
- ISSN :
- 14321963 and 01728113
- Volume :
- 37
- Database :
- OpenAIRE
- Journal :
- Der Pathologe
- Accession number :
- edsair.doi...........24f972b304a1007f90f014ebb66f5b43