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Association between Axial Length and Myopic Maculopathy
Association between Axial Length and Myopic Maculopathy
- Source :
- Ophthalmology Retina. 3:867-873
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- Purpose To assess the association between axial length (AL) and the prevalence of myopic maculopathy in a general Japanese population. Design Population-based cross-sectional study. Participants A total of 2790 Hisayama residents 40 years of age or older who consented to participate and had available data of AL and fundus photographs for the right eyes were enrolled in this study. Methods Myopic maculopathy was defined as the presence of diffuse chorioretinal atrophy, patchy chorioretinal atrophy, or macular degeneration. The optimal cutoff values of axial length for identifying myopic maculopathy were estimated from the receiver operating characteristic curve. The odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using a logistic regression analysis. Main Outcome Measures Odds ratios of AL for prevalent myopic maculopathy and the optimal cutoff values of AL for detecting myopic maculopathy. Results Longer AL was associated significantly with prevalence of myopic maculopathy in both genders. The optimal cutoff values of AL for identifying myopic maculopathy were 25.9 mm in men and 25.3 mm in women. Participants with ALs of these values or longer showed a significantly higher OR for myopic maculopathy than those with AL of less than these values (men: OR, 21.23; 95% CI, 8.74–51.57; women: OR, 38.49; 95% CI, 18.03–86.49). Conclusions The present study found that there was a positive association between AL and the likelihood of myopic maculopathy, and the cutoff levels of AL for identifying myopic maculopathy were 25.9 mm in men and 25.3 mm in women. Our findings suggest that patients with AL close to or longer than these values should undergo intensive treatment and detailed ophthalmic follow-up.
- Subjects :
- medicine.medical_specialty
Visual acuity
genetic structures
Cross-sectional study
Population
03 medical and health sciences
0302 clinical medicine
Ophthalmology
medicine
Cutoff
education
030304 developmental biology
0303 health sciences
education.field_of_study
business.industry
Odds ratio
Macular degeneration
medicine.disease
eye diseases
Confidence interval
030221 ophthalmology & optometry
Maculopathy
sense organs
medicine.symptom
business
Subjects
Details
- ISSN :
- 24686530
- Volume :
- 3
- Database :
- OpenAIRE
- Journal :
- Ophthalmology Retina
- Accession number :
- edsair.doi...........25d5259389c8495c97c03e4df5ce8d42
- Full Text :
- https://doi.org/10.1016/j.oret.2019.04.023