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Codeine Can’t Do It

Authors :
Erica D. Wittwer
Toby N. Weingarten
Katarina Bojanić
Juraj Sprung
Wayne T. Nicholson
Source :
A Case Approach to Perioperative Drug-Drug Interactions ISBN: 9781461474944
Publication Year :
2015
Publisher :
Springer New York, 2015.

Abstract

This case discusses a pharmacokinetic interaction between the prodrug codeine and fluoxetine. Codeine is converted to its active metabolite morphine by cytochrome P450 2D6. Fluoxetine is a 2D6 inhibitor.

Details

ISBN :
978-1-4614-7494-4
ISBNs :
9781461474944
Database :
OpenAIRE
Journal :
A Case Approach to Perioperative Drug-Drug Interactions ISBN: 9781461474944
Accession number :
edsair.doi...........27b5bcba68295942fde08c9bd66ed931