Vitamin G Saturation--Kidney Retention after an Intravenous Test Dose of Ascorbic Acid

Conclusions1. The intravenous test dose method for the determination of Vitamin C saturation in the body by the study of the urinary excretion eliminates the factor of uncertain absorption of the ascorbic acid from the gastro-intestinal tract, but the problem of faulty kidney elimination remains. 2. In order to properly evaluate this factor a study of the blood curve for possible renal retention is essential. 3. A test is outlined which permits a more complete study of Vitamin C saturation. 4. Results illustrating certain types of curves obtained with and without renal retention are presented and interpreted. Thus far retention of Vitamin C has been noted in patients with marked nitrogenous retention only. 5 . All patients with nitrogenous retention do not have Vitamin C retention, but renal retention of Vitamin C may occur. To our knowledge this has not been demonstrated before.