Palladium-Catalyzed Synthesis of Aryl Ketones from Carboxylic Acids and Arylboronic Acids Using EEDQ

with boronic acids or other organoboranes. These methods are mild, efficient, and regioselective. However, there are several limitations of these methods. The acid derivatives are not commercially available and anhydride is inefficient to use because the half part of car-boxylic anhydride is lost as a leaving group. Goosen and his coworkers reported a palladium-catalyzed synthesis of aryl ketones directly by the reaction of boronic acids with active ester or anhydride of carboxylic acid generated