Thieme Chemistry Journal Awardees - Where are They Now? Dibutyltin Dimethoxide Catalyzed N-Nitrosoaldol Reaction of Alkenyl Trichloroacetate

Nitrosoaldol reaction between alkenyl trichloroacetates and nitrosobenzene has been achieved using dibutyltin dimethoxide as a catalyst, which is regenerated in the presence of methanol. The corresponding α-hydroxyamino ketones (N-adducts) have exclusively formed not only from cyclic alkenyl trichloroacetates but also from acyclic ones.