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Intralesional Bleomycin for Acquired Immunodeficiency Syndrome-Associated Cutaneous Kaposi's Sarcoma
Intralesional Bleomycin for Acquired Immunodeficiency Syndrome-Associated Cutaneous Kaposi's Sarcoma
- Source :
- Archives of Dermatology. 131:228
- Publication Year :
- 1995
- Publisher :
- American Medical Association (AMA), 1995.
-
Abstract
- The treatment of acquired immunodeficiency syndrome (AIDS)—associated Kaposi's sarcoma (KS) is controversial. 1 Local treatments include the argon laser, 2 cryotherapy, 3 and intralesional vinblastine. 3 We report our experience with intralesional bleomycin used in the treatment of cutaneous KS. Methods. Since September 1987, two observers used intralesional bleomycin to treat 15 men with biopsyproven AIDS-associated KS. The median age was 35 years (range, 29 through 63 years). The known risk factor was homosexuality in nine cases and not known in six cases. At inclusion, the median CD4 cell count in 13 patients was 199×10 9 /L (range, 1 to 634×10 9 /L) Cutaneous lesions (not previously treated) were located on both the face and the body. The size of the lesions ranged from 2 to 15 mm. Both macular and nodular lesions were observed. The median number of lesions treated per patient was eight (range, one through 19). Two
- Subjects :
- medicine.medical_specialty
business.industry
medicine.medical_treatment
Cryotherapy
Dermatology
General Medicine
medicine.disease
Bleomycin
Vinblastine
Surgery
chemistry.chemical_compound
chemistry
Acquired immunodeficiency syndrome (AIDS)
medicine
Sarcoma
Cd4 cell count
Risk factor
business
Kaposi's sarcoma
medicine.drug
Subjects
Details
- ISSN :
- 0003987X
- Volume :
- 131
- Database :
- OpenAIRE
- Journal :
- Archives of Dermatology
- Accession number :
- edsair.doi...........2931cc1326e417963bf2138243cfaca7
- Full Text :
- https://doi.org/10.1001/archderm.1995.01690140114026