CALIBRATE: Intensive profiling of circulating tumour DNA (ctDNA) from patients participating in experimental therapeutics trials including mutational profiles and copy number changes

Authors :: William Dott
Carlos Caldas
James D. Brenton
Sanjeev Kumar
Maricica Zabrautanu
Hedley Carr
Nitzan Rosenfeld
Francesco Marrass
Javier Garcia-Corbacho
Mirela Hategan
Brian Dougherty
James Anthony Morris
Richard D. Baird
Davina Gale
Duncan I. Jodrell
Florent Mouliere
Elizabeth A. Harrington
J. Carl Barrett
Bristi Basu
Simon Pacey
Source :: Journal of Clinical Oncology. 34:11530-11530
Publication Year :: 2016
Publisher :: American Society of Clinical Oncology (ASCO), 2016.
Abstract: 11530Background: Serial analysis of plasma ctDNA with next generation sequencing could be used to identify patients for matched molecular therapies, to monitor the relative abundance of mutations o...

Subjects :: Cancer Research
chemistry.chemical_compound
Oncology
chemistry
business.industry
Profiling (information science)
Medicine
Computational biology
business
DNA
DNA sequencing

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