790 Rehabilitation of long-term survivors after Hodgkin's disease: A cross-sectional study in Calvados, France

With the growing number of patients surviving cancer, there is an increasing concern with their long-term adaptation. A cross-sectional study was performed in 1995 focusing on physical, psychological, social and familial sequelae in Hodgkin's disease patients who survived 4 years or more from initial treatment. Patients were selected from the Calvados General Cancer Registry if they were treated during the 1978–1990 period, did not develop a second malignancy, remained free of disease since 01.01.1991, and were aged 18 years or more at interview. Information was taken from a self questionnaire sent by mail. The EORTC QLQ-C30 core questionnaire was used to evaluate the quality of life. Clinical data were obtained from medical records. At March 1st, 1995,107 patients (male/female ratio 1.4; mean age 32 years, range 3 to 78) were selected of whom 67% presented with early stages, 38% with B symptoms. Initial therapy consisted of irradiation (RT) in 29%, combination RT and chemotherapy (CT, mostly MOPP) in 66%, and CT alone in 5%. The mean follow-up was 123 months (57 to 203). Overall, 59% of patients developed mild (27%), moderate (25%) or severe (7%) clinical complications. Complications did not correlate with follow-up, clinical stage and RT extent In contrast, complications correlated with CT ( P = 0.058), independently of RT. Results concerning the survey and the quality of life in these patients will be presented.