Advances in treatment of cutaneous and subcutaneous vascular anomalies by pulsed dual wavelength 595- and 1064-nm application

The Cynergy™ vascular workstation with MultiPlex™ technology (Cynosure, MA, USA) combines 595 nm pulsed dye laser (PDL) with 1064 nm Nd:YAG laser. This is done with a unique machine, having two laser heads, one fiber, and one handpiece. It is a synchronized dual wavelength laser system, with a sequential application of 595 nm PDL- and 1064 nm Nd:YAG-laser irradiation. This device may be more effective than single wavelength lasers because it targets structures at different dermal levels using two different wavelengths. A great deal of interest has been generated recently in methemoglobin formation and the absorption characteristics of a blood clot. In this paper we review our experience with this machine for cutaneous and subcutaneous vascular anomalies (PDL-resistant port-wine stains, venous malformations, telangiectasia, hyperkeratotic vascular anomalies, hemangiomas, angiolymphoid hyperplasia with eosinophilia).