Back to Search
Start Over
A simple hydrazone probe for recognition of Al3+ and PPi and its applicability in lysosomal imaging
- Source :
- Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 268:120680
- Publication Year :
- 2022
- Publisher :
- Elsevier BV, 2022.
-
Abstract
- A simple hydrazone probe (1) was designed and synthesized for the successive detection of Al3+ and pyrophosphate (PPi) in almost 100% buffer environment. The probe provided O2N donor set for chelation with Al3+, leading to a distinct fluorescence boost at 510 nm. The in-situ formed 1-Al3+ complex detected PPi with an “on-off” behavior. The detection limits for Al3+ and PPi were 35.7 nM and 76 nM, respectively. Benefiting from the existence of morpholine as lysosome-targeting group, probe 1 was successfully applied to the detection of Al3+ and PPi in lysosomes.
Details
- ISSN :
- 13861425
- Volume :
- 268
- Database :
- OpenAIRE
- Journal :
- Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
- Accession number :
- edsair.doi...........2bc7a56ad71f3521a4ab35a5be41ea0d