Bone turnover in long-term survivors of childhood acute lymphoblastic leukemia

Background We investigated the effects of demographic, lifestyle (self-reported smoking status and physical activity levels), cancer-related treatment factors (radiation and chemotherapy), and diet (calcium and vitamin D intake) on bone turnover and the relationship of bone turnover to lumbar spine bone mineral density (BMD) Z-scores (LS-BMD Z-scores) determined by Quantitative Computed Tomography (QCT) in 418 ≥5-year survivors of childhood acute lymphoblastic leukemia (ALL).