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Abstract WP154: Low-field Portable Mri For Routine Post-thrombectomy Assessment Of Ongoing Brain Injury

Authors :
Nanthiya Sujijantarat
Andrew Koo
Ivan Jambor
Ajay Malhotra
Anna Crawford
Mercy Mazurek
Nethra Parasuram
Vineetha Yadlapalli
Isha R Chavva
Joseph Antonios
Aladine Elsamadicy
Daniela Renedo
Ryan Hebert
Joseph L Schindler
Lauren H Sansing
Adam H De Havenon
Madelynne Olexa
Juan E Iglesias
Matthew Rosen
W Taylor T Kimberly
Nils H Petersen
Kevin N Sheth
Charles Matouk
Source :
Stroke. 54
Publication Year :
2023
Publisher :
Ovid Technologies (Wolters Kluwer Health), 2023.

Abstract

Introduction: Conventional MRI (cMRI) is not routinely available post-mechanical thrombectomy (MT), which can preclude accurate infarction assessment. Our objective was to evaluate the use of low-field portable MRI (pMRI) for bedside evaluation post-MT, including its use as a post-procedural baseline monitor. Methods: Low-field pMRI was used to obtain bedside imaging in post-MT patients between December 2021 to August 2022 at Yale-New Haven Hospital. All pMRI exams were conducted in the standard ferromagnetic environment of the IR suite. Volumetric analyses were performed by a neuroradiologist using 3D Slicer software. If cMRI was not available for comparison, a CT was used. Patients’ charts were reviewed for pre-revascularization MAP and occurrences of MAP dropping by 10% and 20% from individual baselines between the time of pMRI and delayed imaging. Results: A total of 25 patients (64% females, median age 77 years-old [IQR 69.5-84.5]) underwent bedside pMRIs in the IR suite post-MT. The median time from last known normal to access was 6 hours [IQR 4-17]. The median pMRI examination time was 30 minutes [IQR 17-32]. Of the 24 patients with available delayed imaging, 7 (29.2%) had infarct progression compared to immediate post-MT pMRI, while 15 patients (62.5%) had stable/decreased stroke volume. Two patients (8.3%) had parenchymal hemorrhage type 2 and were excluded from further analysis. There was no statistically significant difference between the proportions of favorable TICI scores (85.7% in the infarct progression group vs. 92.3% in the stable/decreased infarct group, p=1.00). Patients with infarct progression had comparable pre-revascularization MAP compared to those with stable/decreased delayed infarct volume (mean of 100.3±4.6 vs. 101.9±15.9 respectively, p=0.727) but had more occurrences of MAP dropping by 10% and 20% of their baseline between the time of pMRI and delayed imaging (mean of 35.0±23.3 vs. 14.7±11.3 occurrences, p=0.011; and mean of 21.7±16.5 vs. 8.5±9.5 occurrences, p=0.026, respectively). Conclusions: The use of low-field MRI in the post-MT setting can facilitate benchmark brain monitoring and serial examinations to evaluate the impact of potential physiological perturbations that may impact ongoing brain injury.

Details

ISSN :
15244628 and 00392499
Volume :
54
Database :
OpenAIRE
Journal :
Stroke
Accession number :
edsair.doi...........2de7b738f686e19fc12b0f79da48449b
Full Text :
https://doi.org/10.1161/str.54.suppl_1.wp154