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In vivo Evaluation of Antimalarial and Cytotoxic Properties of Crude Aqueous Extract of the Fruiting Body of Medicinal Mushroom, Ganoderma lucidum (W.Curt.:Fr.) P. Karst in Plasmodium berghei-Infected Mice

In vivo Evaluation of Antimalarial and Cytotoxic Properties of Crude Aqueous Extract of the Fruiting Body of Medicinal Mushroom, Ganoderma lucidum (W.Curt.:Fr.) P. Karst in Plasmodium berghei-Infected Mice

Authors :
George O. Eidangbe
Kayode E. Adebisi
Olarewaju M. Oluba
A. A. Odutuga
E. Chukwu Onyeneke
Source :
Journal of Immunological Techniques in Infectious Diseases.
Publication Year :
2013
Publisher :
OMICS Publishing Group, 2013.

Abstract

In vivo Evaluation of Antimalarial and Cytotoxic Properties of Crude Aqueous Extract of the Fruiting Body of Medicinal Mushroom, Ganoderma lucidum (W.Curt.:Fr.) P. Karst in Plasmodium berghei-Infected Mice This study was aimed at investigating the in vivo antimalarial and cytotoxic activities of crude aqueous extracts of the fruiting bodies of Ganoderma lucidum, a mushroom with well established medicinal properties. Plasmodium berghei (1×107) was inoculated intraperitoneally into Swiss albino mice. The extract was then administered by an intra gastric tube once daily for four days starting from the day of parasite inoculation. Chloroquine (CQ) (used as standard drug), was administered through the same route.

Details

ISSN :
23299541
Database :
OpenAIRE
Journal :
Journal of Immunological Techniques in Infectious Diseases
Accession number :
edsair.doi...........2f17e9c495f2c55d0614470ace7f9e1d
Full Text :
https://doi.org/10.4172/2329-9541.1000116