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Modeling Cardiac Mechanics on a Sub-Cellular Scale

Authors :
Joakim Sundnes
Samuel T. Wall
Åshild Telle
Source :
Modeling Excitable Tissue ISBN: 9783030611569
Publication Year :
2020
Publisher :
Springer International Publishing, 2020.

Abstract

We aim to extend existing models of single-cell mechanics to theEMIframework, to define spatially resolved mechanical models of cardiac myocytes embedded in a passive extracellular space. The models introduced here will be pure mechanics models employing fairly simple constitutive laws for active and passive mechanics. Future extensions of the models may include a coupling to the electrophysiology and electro-diffusion models described in the other chapters, to study the impact of spatially heterogeneous ion concentrations on the cell and tissue mechanics.

Details

ISBN :
978-3-030-61156-9
ISBNs :
9783030611569
Database :
OpenAIRE
Journal :
Modeling Excitable Tissue ISBN: 9783030611569
Accession number :
edsair.doi...........2fbd291bed86af236ee737fabb5389a6
Full Text :
https://doi.org/10.1007/978-3-030-61157-6_3