Corrected transposition of the great arteries and dextrocardia: a case of prenatal diagnosis of these rare anomalies and literature review

The case of prenatal ultrasound diagnosis of combination corrected transposition of the great arteries (cTGA) with dextrocardia at 21 weeks of gestation is presented. The high-level ventricular septal defect and stenosis of pulmonary artery were associated cardiac pathologies. Another anomalies of the fetus were not detected. The fetus karyotype was normal, defined by classical cytogenetic analysis. The prenatal consultation assessed the prognosis for life and health as unfavorable. According to patient’s decision the pregnancy was terminated. Literature review of antenatal diagnostics of cTGA and combined cTGA with dextrocardia and the matters of short- and long-term prognosis for the fetus were presented in the paper. The issues of the difficulty of detecting cTGA in a fetus and prenatal counseling is discussed, especially in the presence of an abnormality of the intrathoracic location of the heart.