Secretion of Radioactivity in Milk Fat after a Single Oral Dose of (3H)Myristic Acid to a Goat

ABS>Tritium-labeled myristic acid was administered orally as free acid to a lactating goat, and then the secretion of the radioactivity in the total milk lipids and milk glyceride fatty acids was followed for thirteen days. Measurable activity was found in the milk fat 4 hr after administration and the maximum specific activity occurred within 25 hr. About 10% of the radioactivity administered was recovered during the experimental period, and about 25% of the activity collected during 13 days was secreted in the first 28 hr. In the beginning the nonvolatile fatty acids had a higher specific activity than the volatile fatty acids, and there seemed to be a tendency for the specific activities in the short chain acids to increase with time; whereas the long-chain acids appeared to be less active later in the experiment. (auth)