Structure and Biology of Self Lipid Antigens

Authors :: Lucia Mori
G. De Libero
Source :: Current Topics in Microbiology and Immunology ISBN: 9783540695103
Publication Year :: 2007
Publisher :: Springer Berlin Heidelberg, 2007.
Abstract: Self lipid antigens induce selection and expansion of autoreactive T cells which have a role in immunoregulation and disease pathogenesis. Here we review the important biological rules which determine lipid immunogenicity. The impact of lipid structure, synthesis, traffic, membrane distribution and CD1 loading are discussed.

Subjects :: Immunogenicity
T-cell receptor
Phospholipid
CD1
chemical and pharmacologic phenomena
Biology
complex mixtures
Cell biology
Pathogenesis
chemistry.chemical_compound
Immune system
chemistry
Antigen
Immunology
lipids (amino acids, peptides, and proteins)
Late endosome

ISBN :: 978-3-540-69510-3
ISBNs :: 9783540695103
Database :: OpenAIRE
Journal :: Current Topics in Microbiology and Immunology ISBN: 9783540695103
Accession number :: edsair.doi...........30b182d9360cdf8a3eb84f81ead7fa90
Full Text :: https://doi.org/10.1007/978-3-540-69511-0_3