Back to Search
Start Over
The Woven EndoBridge device for ruptured intracranial aneurysms: international multicenter experience and updated meta-analysis
- Source :
- Neuroradiology. 63:1891-1899
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- The Woven EndoBridge (WEB) can be used to treat wide-necked aneurysms without antiplatelet medications, suggesting it may have advantages in the setting of aneurysmal subarachnoid hemorrhage (aSAH). The goal was assessment of safety and efficacy of WEB in aSAH given the delayed nature of aneurysmal thrombosis. An international retrospective analysis of patients with aSAH treated with WEB was conducted at 7 tertiary centers from 2016 to 2020. Outcomes included rates of rebleeding, retreatment, complications, and complete occlusion. Furthermore, a systematic review and meta-analysis was conducted from 2011 to 2020 assessing the same outcomes. All pooled event rates were calculated using a random effect model. Consecutive patients with aSAH harbored 25 aneurysms that were treated with 29 WEB devices. The mean age was 53 years, and 65% were female. Zero experienced rebleeding, 2 were retreated, 2 experienced complications, 16 were completely occluded at 3 months, and 21 were completed occluded at 9–12 months. Meta-analysis of 309 WEB treatments for aSAH from 7 case series revealed 2.5% (95% CI 1–5%) had rebleeding, 9% (95% CI 4–17%) were retreated, 17% (95% CI 10–30%) had complications, and 61% (95% CI 51–71%) were completely occluded at 3–6 months. WEB embolization in the setting of aSAH provides similar protection against rebleeding with comparable retreatment rates to traditional approaches. However, there is a higher rate of incomplete radiographic occlusion and operative complications compared to WEB embolization of unruptured aneurysms. Long-term prospective studies are needed to fully delineate the role of WEB embolization in aSAH.
- Subjects :
- medicine.medical_specialty
Subarachnoid hemorrhage
business.industry
medicine.medical_treatment
education
medicine.disease
Thrombosis
030218 nuclear medicine & medical imaging
Surgery
03 medical and health sciences
0302 clinical medicine
Meta-analysis
Occlusion
medicine
Radiology, Nuclear Medicine and imaging
Neurology (clinical)
Neurosurgery
Embolization
Cardiology and Cardiovascular Medicine
business
Prospective cohort study
030217 neurology & neurosurgery
Neuroradiology
Subjects
Details
- ISSN :
- 14321920 and 00283940
- Volume :
- 63
- Database :
- OpenAIRE
- Journal :
- Neuroradiology
- Accession number :
- edsair.doi...........3146082afb21fcca612c90262f23f34b