Refractory hypercalcemia: Unusual presentation for diffuse large B cell lymphoma

Patients with diffuse large B cell lymphoma can occasionally develop hypercalcemia but it is rare at the onset of disease. We present a case of an elderly female who presented with refractory hypercalcemia, workup of which led to the diagnosis of B cell lymphoma. We discuss about various etiologies for development of hypercalcemia in a patient with lymphoma or leukemia.