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The application of synchrotron radiation to non-invasive angiography

The application of synchrotron radiation to non-invasive angiography

Authors :
U. Meyer-Berkhout
R. S. Kernoff
J. N. Otis
George Brown
J. P. Stone
L. E. Campbell
Donald C. Harrison
Edward Rubenstein
Robert Hofstadter
S. L. Wilson
A.C. Thompson
H. D. Zeman
J. Rolfe
E. B. Hughes
Source :
Nuclear Instruments and Methods in Physics Research. 208:665-675
Publication Year :
1983
Publisher :
Elsevier BV, 1983.

Abstract

Synchrotron radiation provides a new source of X-rays highly-suited to iodine K-edge Digital Subtraction Angiography (DSA). The use of such beams provides maximum sensitivity to intra-arterial iodine and virtually eliminates image contrast due to non-vascular body structures. The intensity of the beams permits short exposure times and allows images to be recorded, in line-scan fashion, in sharp focus despite arterial motions. The sensitivity of this method offers the prospect of visualizing arteries, and in particular the coronary arteries, by peripheral venous injection. The principles of DSA have been demonstrated using phantoms and excised animal hearts, and in vivo studies in animals have begun. The instrumentation developed for this purpose and the results obtained to date are summarized.

Details

ISSN :
01675087
Volume :
208
Database :
OpenAIRE
Journal :
Nuclear Instruments and Methods in Physics Research
Accession number :
edsair.doi...........3494d10ae391dbff91952f9c01f8a28d
Full Text :
https://doi.org/10.1016/0167-5087(83)91202-4