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ChemInform Abstract: Intramolecular Dehydrative Coupling of Tertiary Amines and Ketones Promoted by KO-t-Bu/DMF: A New Synthesis of Indole Derivatives

Authors :
Shao-zhen Nie
Xue-jiao Dong
Ming Yan
Yan-yan Chen
Xue-jing Zhang
Wen-Tao Wei
Source :
ChemInform. 45
Publication Year :
2014
Publisher :
Wiley, 2014.

Abstract

A new synthesis of indole derivatives has been achieved through intramolecular dehydrative coupling of tertiary amines and ketones promoted by KO-t-Bu/DMF. The reaction probably proceeds via an α-amino alkyl radical pathway.

Details

ISSN :
09317597
Volume :
45
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........35478f1dad101f4a82a136a6038242c5
Full Text :
https://doi.org/10.1002/chin.201419166