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ChemInform Abstract: Exploring the Vinylogous Reactivity of Cyclohexenylidene Malononitriles: Switchable Regioselectivity in the Organocatalytic Asymmetric Addition to Enals Giving Highly Enantioenriched Carbabicyclic Structures

ChemInform Abstract: Exploring the Vinylogous Reactivity of Cyclohexenylidene Malononitriles: Switchable Regioselectivity in the Organocatalytic Asymmetric Addition to Enals Giving Highly Enantioenriched Carbabicyclic Structures

Authors :
Andrea Sartori
Giorgio Pelosi
Giovanni Casiraghi
Vincenzo Zambrano
Gloria Rassu
Luca Dell'Amico
Claudio Curti
Lucia Battistini
Franca Zanardi
Source :
ChemInform. 46
Publication Year :
2015
Publisher :
Wiley, 2015.

Abstract

A two-step, one-pot sequence under chiral amine—NHC catalysis allows the approach to spiro[4.5]decanone structures in a diastereoselective manner with high e.e.

Details

ISSN :
09317597
Volume :
46
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........357c1f7a098b11d6bd1d6fc82cc6a64e
Full Text :
https://doi.org/10.1002/chin.201509070