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Enantioselective radical-mediated reduction of α-iodolactone using tributyltin hydride in the presence of a chiral amine and a Lewis acid
- Source :
- J. Chem. Soc., Chem. Commun.. :481-482
- Publication Year :
- 1995
- Publisher :
- Royal Society of Chemistry (RSC), 1995.
-
Abstract
- Enantioselective radical-mediated reduction of α-methoxymethyl-α-iododihydrocoumarin 1 using tributyltin hydride is realized in up to 62% enantiomeric excess (e.e.)(88% chemical yield) by combination of chiral diamine 2 and magnesium iodide.
Details
- ISSN :
- 00224936
- Database :
- OpenAIRE
- Journal :
- J. Chem. Soc., Chem. Commun.
- Accession number :
- edsair.doi...........35d3e25995865ae290e0ba8fc050cb66
- Full Text :
- https://doi.org/10.1039/c39950000481