New methods and reagents in organic synthesis. 47. A general, efficient, and convenient synthesis of diarylheptanoids

Authors :: Nobuharu Kato
Yasumasa Hamada
Takayuki Shioiri
Source :: Chemical and Pharmaceutical Bulletin. 32:3323-3326
Publication Year :: 1984
Publisher :: Pharmaceutical Society of Japan, 1984.
Abstract: An efficient synthesis of physiologically interesting diarylheptanoids has been carried out through direct C-acylation using diethyl phosphorocyanidate (DEPC) followed by Grignard reactions with aldehydes.

Subjects :: chemistry.chemical_classification
integumentary system
Chemistry
Carboxylic acid
Diarylheptanoid
Grignard reaction
General Chemistry
General Medicine
Acylation
chemistry.chemical_compound
Reagent
Drug Discovery
Organic chemistry
Organic synthesis
Aliphatic compound
Diarylheptanoids

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