Inhibitory of PANC-1 produced by Indonesian’s Marine Sponge Endectyon delaubenfelsi Adapted to Nutrient Starvation

The bioactivity of Indonesian Marine Sponge Endectyon delaubenfelsi has been conducted on July 2018. The active metabolite based on bioassay guided-separation with several steps of chromatography. The FTIR spectrum shows that the active metabolite has N-H amine functional groups at 3434.6 cm−1 C-H methyl was detected at 3090.46 cm−1, and the fingerprint region at 1637.27 cm−1 as C-N imine. Based on the FTIR data shows indicate that the active compound as alkaloid. Metabolite active has activity IC50 = 0.2 ug / mL indicates that the active compound from of Endectyon delaubenfelsi has potential activity as the new model to the drug discovery against PANC-1 cell.