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Efficient N- and C-functionalisation of cyclam macrocycles utilising bisaminal methodology

Authors :
Stephen J. Archibald
Ross W. Boyle
Elizabeth A. Lewis
Cheryll C. Allan
Source :
Tetrahedron Letters. 45:3059-3062
Publication Year :
2004
Publisher :
Elsevier BV, 2004.

Abstract

An efficient synthesis of C-functionalised cyclam macrocycles that employs bisaminal intermediates and allows N-substitution to be controlled is reported.

Details

ISSN :
00404039
Volume :
45
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........3781aa095e0144cc0c940a667fd9dda3
Full Text :
https://doi.org/10.1016/j.tetlet.2004.02.108