TNF-α-induces airway hyperresponsiveness to cholinergic stimulation in guinea pig airways

Authors :: Rajesh Makwana
Neil Gozzard
Domenico Spina
Clive P. Page
Source :: British Journal of Pharmacology. 165:1978-1991
Publication Year :: 2012
Publisher :: Wiley, 2012.
Abstract: BACKGROUND AND PURPOSE TNF-α is an inflammatory cytokine implicated in the pathogenesis of asthma and it causes airway inflammation, bronchoconstriction and airway hyperresponsiveness to a number of spasmogens following inhalation.

Subjects :: Pharmacology
Inhalation
business.industry
medicine.medical_treatment
Inflammation
Stimulation
respiratory system
respiratory tract diseases
Pathogenesis
Cytokine
Immunology
medicine
Cholinergic
Bronchoconstriction
Tumor necrosis factor alpha
medicine.symptom
business

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