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ChemInform Abstract: Platelet Glycoprotein IIb/IIIa Receptor Antagonists Derived from Isoxazolidines
- Source :
- ChemInform. 30
- Publication Year :
- 2010
- Publisher :
- Wiley, 2010.
-
Abstract
- A series of isoxazolidines has been synthesized as mimetics of the RGD sequence and was evaluated as antagonists of the platelet glycoprotein IIb/IIIa receptor. These compounds were shown to be highly potent GPIIb/IIIa antagonists, exhibiting submicromolar potencies.
Details
- ISSN :
- 15222667 and 09317597
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- ChemInform
- Accession number :
- edsair.doi...........38ecd44f33e4e57341d369004b2dfa90
- Full Text :
- https://doi.org/10.1002/chin.199919146