A NEW THEORY ON THE FORMATION OF RENAL ALCULI1

SUMMARY 1. This paper presents a new theory on the formation and growth of urinary calculi based on the lymphatic drainage of the kidney which is described. 2. The material and methods which have been used in studying the formation of renal calculi have been described in detail. These include the technique of microradiography. 3. The current theories of stone formation from the smallest crystalline deposits are reviewed. 4. Observations have been made which are not explained by Randall's theory. 5. By the new theory all the observed facts, including the formation of Randall's plaques, can be explained. 6. Diffraction X-ray analysis has been used to support this new theory. 7. Facts of importance in partial nephrectomy in the treatment of renal lithiasis are emphasised and explained.