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Synthesis of indole-3-carboxamides via a haloform cleavage reaction of 3-trifluoroacetylindole with lithium dialkylamides

Authors :
Gordon W. Gribble
Richard M. Soll
Heidi L. Hassinger
Source :
Tetrahedron Letters. 39:3095-3098
Publication Year :
1998
Publisher :
Elsevier BV, 1998.

Abstract

Reaction of 3-trifluoroacetylindole ( 4 ) with lithium dialkylamides affords the corresponding indole-3-carboxamides ( 5 ) in good to excellent yields.

Details

ISSN :
00404039
Volume :
39
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........39caafe1d04659a98699c41b5982317d
Full Text :
https://doi.org/10.1016/s0040-4039(98)00505-x