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Dependence of Counterion Binding on DNA Shape as Determined By Counterion Condensation Theory

Authors :
Wilma K. Olson
Marcia O. Fenley
Gerald S. Manning
Source :
Macromolecules. 33:1899-1903
Publication Year :
2000
Publisher :
American Chemical Society (ACS), 2000.

Abstract

We have computed the fraction of DNA phosphate charge neutralized by condensed counterions for parallel pairs of linear DNA segments, DNA circles, and representative closed-circular supercoiled DNA configurations ranging in length from 42 to 3000 base pairs. We find significant but small uptake of condensed counterions for the more compact structures relative to an isolated linear DNA segment.

Details

ISSN :
15205835 and 00249297
Volume :
33
Database :
OpenAIRE
Journal :
Macromolecules
Accession number :
edsair.doi...........3b1b5e0bf6f8d231ee3787f4fd0b79fa
Full Text :
https://doi.org/10.1021/ma990191u