Patient-derived Fab structures suggest mechanism by which affinity maturation promotes autoantibody recognition of MuSK in the autoimmune disease myasthenia gravis

Authors :: Kevin C. O’Connor
Rachel L. Redler
Steven J. Burden
Damian C. Ekiert
Casey Vieni
Miriam L. Fichtner
Ljuvica Kolich
Source :: Acta Crystallographica Section A Foundations and Advances. 76:a106-a106
Publication Year :: 2020
Publisher :: International Union of Crystallography (IUCr), 2020.

Subjects :: Autoimmune disease
Chemistry
Mechanism (biology)
Autoantibody
Condensed Matter Physics
medicine.disease
Biochemistry
Myasthenia gravis
Inorganic Chemistry
Affinity maturation
Structural Biology
Immunology
medicine
General Materials Science
Physical and Theoretical Chemistry

Tools