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Label-Free Mass Quantitation of Individual Cathepsin K Enzymes using Interferrometric Scattering Microscopy

Authors :
Edward R. Grant
Luke Melo
Dieter Brömme
Matthew Kowal
Pierre-Marie Andrault
Source :
Imaging and Applied Optics Congress.
Publication Year :
2020
Publisher :
Optica Publishing Group, 2020.

Abstract

Interferrometric scattering microscopy is used to mass quantify individual Cathepsin K enzymes in solution. Treatments for osteoporosis are assessed by monitoring the oligomerization of Cathepsin K.

Details

Database :
OpenAIRE
Journal :
Imaging and Applied Optics Congress
Accession number :
edsair.doi...........3be4c233355f41ea04f7e68a2f4cecf9
Full Text :
https://doi.org/10.1364/3d.2020.jth2a.30