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Ophthalmological findings in patients with leukaemia in a Colombian population
- Source :
- Archivos de la Sociedad Española de Oftalmología (English Edition). 96:242-250
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Objective To report the ocular manifestations in patients with leukaemia. Methods This is a retrospective, descriptive and observational study in patients with ocular manifestations of leukaemia. Results A total of 14 eyes were evaluated corresponding to 8 patients (5 women and 3 men) with ocular manifestations of leukaemia. The mean age at diagnosis was 43 years (31–76 years). Six eyes corresponded to patients with Acute Myeloid Leukaemia (AML), four eyes to Acute Lymphoid Leukaemia (ALL), two eyes to Chronic Myeloid Leukaemia (CML), and the remaining two belonged to patients with Hairy Cell Leukaemia (HCL). The primary ocular findings were choroidal invasion in 12 eyes (85.7%), retinal infiltration in 4 eyes (28.6%), and neuro-ophthalmic disorders in 4 eyes (28.6%). The mean visual acuity improved from 0.689 to 0.449 (logMAR) (P = .012) after the systemic and intrathecal chemotherapy. Of the eight patients, four died from systemic complications of the underlying disease. Conclusions This is the first report of multiple ocular manifestations secondary to leukaemia in a Colombian population. It is important to keep in mind that this disease is included within the masquerade syndromes and that the ophthalmological findings that, while subtle, can also be devastating and be signs of a life-threatening disease.
- Subjects :
- medicine.medical_specialty
Visual acuity
genetic structures
business.industry
Hairy cell leukaemia
General Medicine
Disease
Dermatology
eye diseases
Masquerade syndrome
03 medical and health sciences
Colombian population
0302 clinical medicine
Acute lymphoid leukaemia
hemic and lymphatic diseases
030221 ophthalmology & optometry
Medicine
In patient
sense organs
medicine.symptom
Myeloid leukaemia
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 21735794
- Volume :
- 96
- Database :
- OpenAIRE
- Journal :
- Archivos de la Sociedad Española de Oftalmología (English Edition)
- Accession number :
- edsair.doi...........3cd6ad2aecea37bb25faca9aeb29965f