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Surgical margins and oncologic results after carcinoma of the external auditory canal

Authors :
Martin Durisin
Hendrik A. Wolff
Bernhard G. Weiss
Friedrich Ihler
Mario Koopmann
Leif Hendrik Dröge
Daniel Weiß
Martin Canis
Hans Christiansen
Source :
The Laryngoscope. 125:2107-2112
Publication Year :
2015
Publisher :
Wiley, 2015.

Abstract

Objectives/Hypothesis External auditory canal cancer is rare and carries a poor prognosis. To date, only a few studies provide evidence for clinical decision making in multimodal treatment. Methods Retrospective chart review of 36 cases in three tertiary referral centers. Results Thirteen patients were treated by surgery alone, 18 by surgery with adjuvant chemoradiotherapy (CRT) and five by primary CRT. Clear surgical margins (R0) were obtained in 19 patients and positive margins (R1) in 12. The 5-year overall survival and local control rates were 59.4% and 74.2% with R0 status versus 56.6% and 26.3% with R1 status. The 5-year overall survival and local control rates were 46.2% and 70.7% with surgery alone, 78.1% and 43.2% with surgery and adjuvant CRT, and 25.0% and 80.0% with primary CRT. Conclusion Surgery is integral to the management of external auditory canal cancer, whereas CRT is necessary as an adjuvant or primary treatment, depending on tumor stage. Level of Evidence 4. Laryngoscope, 125:2107–2112, 2015

Details

ISSN :
0023852X
Volume :
125
Database :
OpenAIRE
Journal :
The Laryngoscope
Accession number :
edsair.doi...........3ead8dd140a5dea0b4c6e5dac41a139f
Full Text :
https://doi.org/10.1002/lary.25381