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Nonlinear Behaviors in Gene Therapy Theoretical and experimental aspects

Authors :
Elena Simona Bacaita
Mariana Pinteala
Carmen Anton
Sorin Trocaru
Valentin Stelian Dragan
Irina Crumpei Tanasa
Gabriela Cioca
Simona Ruxandra Volovat
Iuliana Oprea
Source :
Materiale Plastice. 55:340-343
Publication Year :
2018
Publisher :
Revista de Chimie SRL, 2018.

Abstract

Gene therapy represents a promising method for treating genetic disorders or diseases consisting in the transfer of genetic material (DNA) to cells in order to substitute or to slow down the evolution of the defective gene in cells. Theoretical models to predict DNA release are difficult to build in the classical approach of continuous and differentiable physical quantities, due to the high number of interdependent phenomena that occur simultaneous. The article presents a theoretical model based on the fractal theory of motions in the form of Scale Relativity Theory to describe nonlinear behaviors in gene therapy. Correlations of the theoretical model with experimental data are also observed.

Details

ISSN :
26688220 and 00255289
Volume :
55
Database :
OpenAIRE
Journal :
Materiale Plastice
Accession number :
edsair.doi...........3ec2dc51a1bdd41a4457343ec8351cbb
Full Text :
https://doi.org/10.37358/mp.18.3.5025