THE EFFECT OF ANTLIONS EXTRACT TOWARDS BLOOD GLUCOSE LEVEL OF MALE SWISS MICE INDUCED BY STREPTOZOTOCIN

Background : Diabetes mellitus is a disease that is included in the group of metabolic diseases, characterized by hyperglycemia that occurs due to abnormal insulin secretion. Generally, treatment of diabetes mellitus uses insulin injection and Oral Hypoglycemic Drugs (OHD). In addition there are also animals are trusted by public in healing diabetes mellitus. Antlions (Myrmeleon sp) is a useful animal to treat diabetes mellitus. The body of antlions contains sulfonylureas which is a substance that stimulates insulin secretion in pancreatic beta cells. Aim : The objective of this research was to analyze the effect of antlions extract on blood glucose level of male swiss mice induced by streptozotocin Methods: This research was a pure experimental laboratory study and the design used is the Pre Test and Post Test Control Group Design, which is done by comparing the results of observations in the control and treatment groups after the action was done. Sampling was done using the simple random sampling technique. The sample size used in this study amounted to 30 mice. The data obtained were analyzed using ANOVA test with a confidence level of 95%. Results: The administration of antlions extract could lower (p