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27 REEVALUATION OF 19 CHILDREN ONCE FOUND TO BE DEFICIENT IN SERUM IgA
27 REEVALUATION OF 19 CHILDREN ONCE FOUND TO BE DEFICIENT IN SERUM IgA
- Source :
- Pediatric Research. 13:952-952
- Publication Year :
- 1979
- Publisher :
- Springer Science and Business Media LLC, 1979.
-
Abstract
- The maturation of the serum IgA system is slow in comparison to IgG and IgM. Adult serum IgA levels in normal children are reached only at the age of ten years. The normal range is broad and individual fluctuations marked. To investigate the maturation of the system and the implications of low serum IgA in infections of the respiratory and gastrointestinal tract as well as the ORL system we reexamined 19 children once found in our laboratory to be deficient in serum IgA. We tested serum IgA, IgA and secretory component in tears of these 19 children. 53% of them showed normalization of these parameters, 26 % had low serum IgA while 4 children remained deficient. Maturation and compensatory mechanisms are discussed.
Details
- ISSN :
- 15300447 and 00313998
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- Pediatric Research
- Accession number :
- edsair.doi...........432c11fff9c078b4d2cc6cc30f291c61
- Full Text :
- https://doi.org/10.1203/00006450-197908000-00043