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ChemInform Abstract: Synthesis of 19-[(2-Azido-5-iodo)-benzoyloxy]-LTA4 and Enzymatic Conversion to the LTC4 Analogue

Authors :
Jean-Pierre Vidal
Angelo Sala
Jean-Claude Rossi
Agnes Vidal
Saula Ravasi
Simona Zarini
Thierry Durand
Source :
ChemInform. 31
Publication Year :
2010
Publisher :
Wiley, 2010.

Abstract

New photoaffinity probes based on C-19 position of leukotriene A4 has been synthesized from 19-hydroxy-LTA4 methyl ester. Enzymatic conversion into the LTC4 analogue yielded a potential tool for the study of cys-LT2 receptors.

Details

ISSN :
15222667 and 09317597
Volume :
31
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........44020854b36ba6f0502656ac1ce7679e
Full Text :
https://doi.org/10.1002/chin.200028236