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Palladium-Catalyzed Reductive Coupling of Nitroarenes with Phenols­ leading to N-Cyclohexylanilines

Palladium-Catalyzed Reductive Coupling of Nitroarenes with Phenols­ leading to N-Cyclohexylanilines

Authors :
Huilan Yue
Xin-Sheng Xiao
Kai-Jian Liu
Zilong Tang
Ming Wang
Yi Wang
Xiu-Ling Zeng
Wei-Min He
Yong Zhang
Source :
Synthesis. 50:4637-4644
Publication Year :
2018
Publisher :
Georg Thieme Verlag KG, 2018.

Abstract

A direct and efficient palladium-catalyzed reductive coupling reaction of nitroarenes with phenols has been developed. A series of N-cyclohexylaniline derivatives was easily and efficiently obtained in moderate to good yields via C–N bond formation by the simple use of safe and inexpensive sodium formate as the hydrogen donor.

Details

ISSN :
1437210X and 00397881
Volume :
50
Database :
OpenAIRE
Journal :
Synthesis
Accession number :
edsair.doi...........44042f412db5c4c27ea31863fc52665b
Full Text :
https://doi.org/10.1055/s-0037-1610231