Back to Search
Start Over
Palladium-Catalyzed Reductive Coupling of Nitroarenes with Phenols leading to N-Cyclohexylanilines
Palladium-Catalyzed Reductive Coupling of Nitroarenes with Phenols leading to N-Cyclohexylanilines
- Source :
- Synthesis. 50:4637-4644
- Publication Year :
- 2018
- Publisher :
- Georg Thieme Verlag KG, 2018.
-
Abstract
- A direct and efficient palladium-catalyzed reductive coupling reaction of nitroarenes with phenols has been developed. A series of N-cyclohexylaniline derivatives was easily and efficiently obtained in moderate to good yields via C–N bond formation by the simple use of safe and inexpensive sodium formate as the hydrogen donor.
- Subjects :
- Green chemistry
Hydrogen
010405 organic chemistry
Sodium formate
Organic Chemistry
chemistry.chemical_element
Cyclohexylamine
010402 general chemistry
01 natural sciences
Combinatorial chemistry
Catalysis
Coupling reaction
0104 chemical sciences
chemistry.chemical_compound
chemistry
Phenol
Palladium
Subjects
Details
- ISSN :
- 1437210X and 00397881
- Volume :
- 50
- Database :
- OpenAIRE
- Journal :
- Synthesis
- Accession number :
- edsair.doi...........44042f412db5c4c27ea31863fc52665b
- Full Text :
- https://doi.org/10.1055/s-0037-1610231